Anti-C Reactive Protein抗体[C4] (ab10028)


  • 产品名称Anti-C Reactive Protein抗体[C4]
    参阅全部 C Reactive Protein 一抗
  • 描述
    小鼠单克隆抗体[C4] to C Reactive Protein
  • 特异性This product recognizes only the pentameric C reactive protein. Does not react with Ca2+ depleted protein
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified) (Human).

  • 常规说明

    Concentration varies from lot to lot and can be provided on request.



Our Abpromise guarantee covers the use of ab10028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.


  • 功能Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • 组织特异性Found in plasma.
  • 序列相似性Belongs to the pentaxin family.
    Contains 1 pentaxin domain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Pentraxin 1, short antibody
    • C reactive protein antibody
    • C reactive protein pentraxin related antibody
    • C-reactive protein(1-205) antibody
    • CRP antibody
    • CRP_HUMAN antibody
    • MGC88244 antibody
    • Pentraxin 1 antibody
    • PTX 1 antibody
    • PTX1 antibody
    see all

Anti-C Reactive Protein antibody [C4] 图像

  • Sensitivity to EDTA. Serum samples with (dark blue) and w/o (light blue) Ca2+ ions were tested by two two-site combinations of anti-CRP MAbs. Ab10028 [C4] is sensitive to the conformational changes of CRP molecule and thus the assay gives no signal in the presence of EDTA. Sandwich immunoassay utilizing ab8277 [C2] and ab8278 [C6] recognizes the antigen with the same efficiency in the presence and in the absence of EDTA.

Anti-C Reactive Protein antibody [C4] (ab10028)参考文献

This product has been referenced in:
  • Trilok-Kumar G  et al. Effect of vitamin D supplementation of low birth weight term Indian infants from birth on cytokine production at 6 months. Eur J Clin Nutr 66:746-50 (2012). Read more (PubMed: 22510791) »

See 1 Publication for this product

Product Wall

I have confirmed with the lab and most of our C Reactive Protein antibodies, except C3 and C4, react with both monomer and pentamer form of CRP. (As our clones C3 and C4 do not recognize CRP in the absence of Ca2+ ions, we suggest that they could ...

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We have tested the antibody ab10028 in ELISA only and as it is does not recognize CRP in the absence of Ca2+ ions, so it could not recognize CRP monomer form.
We have not tested ab10028 in western blot so I am sorry we are unable to confirm its sp...

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Thank you for your patience. I am sorry that our system was down yesterday. Further to your enquiry; We have several antibodies that are suitable for sandwich ELISA as a pair. For example; C Reactive Protein antibody [C4] (ab10028) can be pai...

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