The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
Use at an assay dependent dilution.
功能Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol.
通路Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 3/6.
疾病相关Microcephaly, congenital cataract, and psoriasiform dermatitis
序列相似性Belongs to the sterol desaturase family.
结构域The histidine box domains may contain the active site and/or be involved in metal ion binding.