概述

  • 产品名称Anti-BVES抗体
    参阅全部 BVES 一抗
  • 描述
    小鼠单克隆抗体to BVES
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: YSLNDPTLND KKAKKLEHQL SLCTQISMLE MRNSIASSSD SDDGLHQFLR GTSSMSSLHV SSPHQRASAK MKPIEEGAED DDDVFEPASP NTLKVHQLP, corresponding to amino acids 262-361 of Human BVES

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56814 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.
    • 组织特异性Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle.
    • 序列相似性Belongs to the popeye family.
    • 细胞定位Lateral cell membrane. Cell junction > tight junction. Membrane. Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Blood vessel epicardial substance antibody
      • Bves antibody
      • hBVES antibody
      • MGC42413 antibody
      • POP 1 antibody
      • POP1 antibody
      • POPD1_HUMAN antibody
      • POPDC 1 antibody
      • POPDC1 antibody
      • Popeye domain containing 1 antibody
      • Popeye domain containing protein 1 antibody
      • Popeye domain-containing protein 1 antibody
      • Popeye protein 1 antibody
      see all

    Anti-BVES antibody 图像



    • Predicted band size : 41 kDa
      BVES antibody (ab56814) at 1ug/lane + IMR-32 cell lysate at 25ug/lane.

    Anti-BVES antibody (ab56814)参考文献

    ab56814 has not yet been referenced specifically in any publications.

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