Anti-Butyrylcholinesterase抗体(ab82307)

概述

  • 产品名称Anti-Butyrylcholinesterase抗体
    参阅全部 Butyrylcholinesterase 一抗
  • 描述
    兔多克隆抗体to Butyrylcholinesterase
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to an internal region of Human Butyrylcholinesterase, conjugated to KLH

  • 阳性对照
    • A2058 cell line lysate.

性能

应用

Our Abpromise guarantee covers the use of ab82307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Predicted molecular weight: 68 kDa.
ELISA 1/1000.

靶标

  • 功能Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
  • 组织特异性Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
  • 疾病相关Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.
  • 序列相似性Belongs to the type-B carboxylesterase/lipase family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acylcholine acylhydrolase antibody
    • BCHE antibody
    • Butyrylcholine esterase antibody
    • CHE1 antibody
    • CHE2 antibody
    • CHLE_HUMAN antibody
    • Choline esterase II antibody
    • Cholinesterase (serum) 2 antibody
    • Cholinesterase 1 antibody
    • Cholinesterase antibody
    • E1 antibody
    • Pseudocholinesterase antibody
    • Pseudocholinesterase E1 antibody
    see all

Anti-Butyrylcholinesterase antibody 图像

  • Anti-Butyrylcholinesterase antibody (ab82307) at 1/50 dilution + A2058 cell line lysate at 35 µg

    Predicted band size : 68 kDa
    Observed band size : 68 kDa
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

Anti-Butyrylcholinesterase antibody (ab82307)参考文献

ab82307 has not yet been referenced specifically in any publications.

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The BCHE antibody, ab82307is generated from rabbits immunized with a KLH conjugated synthetic peptide between ********* amino acids from the center region of human BCHE.

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