Anti-Butyrylcholinesterase抗体[3E8] (ab17246)

概述

  • 产品名称Anti-Butyrylcholinesterase抗体[3E8]
    参阅全部 Butyrylcholinesterase 一抗
  • 描述
    小鼠单克隆抗体[3E8] to Butyrylcholinesterase
  • 特异性No reaction is seen with acetylcholinesterase from human nervous tissue and erythrocytes.
  • 经测试应用适用于: ELISAmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified) (Human).

性能

应用

Our Abpromise guarantee covers the use of ab17246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/8000.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
    • 组织特异性Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
    • 疾病相关Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.
    • 序列相似性Belongs to the type-B carboxylesterase/lipase family.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Acylcholine acylhydrolase antibody
      • BCHE antibody
      • Butyrylcholine esterase antibody
      • CHE1 antibody
      • CHE2 antibody
      • CHLE_HUMAN antibody
      • Choline esterase II antibody
      • Cholinesterase (serum) 2 antibody
      • Cholinesterase 1 antibody
      • Cholinesterase antibody
      • E1 antibody
      • Pseudocholinesterase antibody
      • Pseudocholinesterase E1 antibody
      see all

    Anti-Butyrylcholinesterase antibody [3E8] (ab17246)参考文献

    ab17246 has not yet been referenced specifically in any publications.

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