The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/200 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
1/100 - 1/500.
Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in neurite outgrowth.
Jiang H et al. PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma. Cancer Med7:869-882 (2018).
Read more (PubMed: 29441724) »