概述

  • 产品名称Anti-BSND抗体
    参阅全部 BSND 一抗
  • 描述
    兔多克隆抗体to BSND
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 211-260 (PNASPHDREE ACSPQQEPQG CRCPLDRFQD FALIDAPTLE DEPQEGQQWE) of Human BSND (NP_476517).

  • 阳性对照
    • Human fetal heart lysate

性能

应用

Our Abpromise guarantee covers the use of ab108150 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
  • 组织特异性Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.
  • 疾病相关Bartter syndrome 4A
  • 细胞定位Cell membrane. Cytoplasm. A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BART antibody
    • Bartter syndrome infantile with sensorineural deafness antibody
    • Bartter syndrome, infantile, with sensorineural deafness (Barttin) antibody
    • Barttin antibody
    • Bsnd antibody
    • BSND_HUMAN antibody
    • deafness, autosomal recessive 73 antibody
    • DFNB 73 antibody
    • DFNB73 antibody
    see all

Anti-BSND antibody 图像

  • Anti-BSND antibody (ab108150) at 1 µg/ml + Human fetal heart lysate at 10 µg

    Predicted band size : 35 kDa

Anti-BSND antibody (ab108150)参考文献

ab108150 has not yet been referenced specifically in any publications.

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