Anti-BRSK1抗体(ab115475)
Key features and details
- Rabbit polyclonal to BRSK1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-BRSK1抗体
参阅全部 BRSK1 一抗 -
描述
兔多克隆抗体to BRSK1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide corresponding to Human BRSK1 (C terminal).
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阳性对照
- Human brain cortex tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab115475于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 87 kDa.
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 87 kDa. |
IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. -
组织特异性
Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle. -
序列相似性
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.
Contains 1 protein kinase domain.
Contains 1 UBA domain. -
细胞定位
Cytoplasm. Nucleus. Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage. - Information by UniProt
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数据库链接
- Entrez Gene: 84446 Human
- Entrez Gene: 381979 Mouse
- Entrez Gene: 499073 Rat
- Omim: 609235 Human
- SwissProt: Q8TDC3 Human
- SwissProt: Q5RJI5 Mouse
- SwissProt: B2DD29 Rat
- Unigene: 182081 Human
see all -
别名
- BR serine/threonine kinase 1 antibody
- BR serine/threonine protein kinase 1 antibody
- BR serine/threonine-protein kinase 1 antibody
see all
图片
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ab115475, at 5µg/ml, staining BRSK1 in formalin-fixed, paraffin-embedded Human brain cortex tissue by immunohistochemistry using a biotinylated anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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Lane 1 : Anti-BRSK1 antibody (ab115475) at 0.5 µg/ml
Lane 2 : Anti-BRSK1 antibody (ab115475) at 1 µg/ml
All lanes : Human brain tissue lysate
Predicted band size: 87 kDa
数据表及文件
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Datasheet download
文献 (0)
ab115475 尚未被引用在任何文献中。