概述

  • 产品名称BRL 54443
  • 描述
    Selective agonist at 5-HT1E and 5-HT1F receptors
  • 生物学描述Potent, high affinity and selective agonist at 5-HT1E/1F receptors (pKi values are 8.7 and 8.9, respectively). Displays >30-fold selectivity for human 5-HT over dopamine receptors (pKi values are 7.2 (5-HT1A), 6.9 (5-HT1B), 7.2 (5-HT1D), 5.9 (5-HT2A), 7.0 (5-HT2B), 6.5 (5-HT2C), 6.3 (D2) and 6.2 (D3)).
  • 纯度> 99%

性能

  • 化学名称5-Hydroxy-3-(1-methylpiperidin-4-yl)-1H-indole
  • 分子量230.31
  • 化学结构Chemical Structure
  • 分子式C14H18N2O
  • CAS编号57477-39-1
  • PubChem识别号2438
  • 存放说明Store at +4°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
  • 溶解度概述Soluble in DMSO to 50 mM
  • 处理

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESCN1CCC(CC1)c2cnc3ccc(O)cc23
  • 来源

    Synthetic

  • 研究领域

    BRL 54443 (ab120627)参考文献

    ab120627 has not yet been referenced specifically in any publications.

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