概述

  • 产品名称BRL 44408 maleate
  • 描述
    Selective α2A adrenoceptor antagonist
  • 生物学描述Selective α2A adrenoceptor antagonist (Ki values are 5.68 and 651 nM for α2A and α2B, respectively). Centrally active following subcutaneous administration. Demonstrates antidepressant and analgesic activity.
  • 纯度> 99%

性能

    BRL 44408 maleate (ab120806)参考文献

    This product has been referenced in:
    • Dwyer JM  et al. Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism. Int J Neuropsychopharmacol 13:1193-205 (2010). Read more (PubMed: 20047711) »
    • Uhlén S  et al. The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors. J Pharmacol Exp Ther 271:1558-65 (1994). Read more (PubMed: 7996470) »

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