概述

  • 产品名称Anti-BRF1抗体
    参阅全部 BRF1 一抗
  • 描述
    兔多克隆抗体to BRF1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 627 and 677 of human BRF1 (NP_001510.2).

  • 阳性对照
    • Human Anaplastic Thyroid Carcinoma, Bladder Cell Carcinoma and Prostate Carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
    • 序列相似性Belongs to the TFIIB family.
      Contains 1 TFIIB-type zinc finger.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B related factor 1 antibody
      • B-related factor 1 antibody
      • BRF antibody
      • BRF-1 antibody
      • brf1 antibody
      • BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) antibody
      • General transcription factor IIIB, 90kD subunit antibody
      • GTF3B antibody
      • hBRF antibody
      • hTFIIIB90 antibody
      • RNA polymerase III antibody
      • subunit 2 antibody
      • TAF3B2 antibody
      • TAF3C antibody
      • TAFIII90 antibody
      • TATA box binding protein (TBP) associated factor 3C antibody
      • TATA box binding protein (TBP) associated factor, RNA polymerase III, GTF3B subunit 2 antibody
      • TATA box-binding protein-associated factor antibody
      • TBP associated factor, RNA polymerase III, 90kD antibody
      • TF3B_HUMAN antibody
      • TF3B90 antibody
      • TFIIIB90 antibody
      • Transcription factor IIIB 90 kDa subunit antibody
      • Transcription initiation factor IIIB antibody
      see all

    Anti-BRF1 antibody 图像

    • ab84560, at a 1/100 dilution, staining BRF1 in formalin fixed, paraffin embedded human prostate carcinoma by Immunohistochemistry, using DAB detection.
    • ab84560, at a 1/500 dilution, staining BRF1 in formalin fixed, paraffin embedded human thyroid carcinoma by Immunohistochemistry, using DAB detection.

    Anti-BRF1 antibody (ab84560)参考文献

    ab84560 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"