Synthetic peptide conjugated to KLH, corresponding to sequence from within amino acids 100-200 of Human BRD2.
A375 cell lysate, Human breast carcinoma.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.09% Sodium Azide
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Protein G purified
This antibody was purified through a protein G column and eluted out with both high and low pH buffers. It was neutralized immediately after elution, followed by dialysis against PBS.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 100 kDa (predicted molecular weight: 88 kDa).
Is unsuitable for IHC-P.
May play a role in spermatogenesis or folliculogenesis.
Contains 2 bromo domains.
Contains 1 ET domain.
One bromodomain is sufficient for a partial interaction with histone H4 acetylated at 'Lys-13'.
Information by UniProt
BRD 2 antibody
Anti-BRD2 antibody (ab37633)参考文献
This product has been referenced in:
et al. Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes. Oncotarget 7:79637-79653 (2016).
Read more (PubMed: 27793034) »
et al. BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells. Oncotarget 6:17698-712 (2015).
Read more (PubMed: 25989842) »
See all 4 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"