Synthetic peptide conjugated to KLH, corresponding to sequence from within amino acids 100-200 of Human BRD2.
A375 cell lysate, Human breast carcinoma.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.09% Sodium Azide
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Protein G purified
This antibody was purified through a protein G column and eluted out with both high and low pH buffers. It was neutralized immediately after elution, followed by dialysis against PBS.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 100 kDa (predicted molecular weight: 88 kDa).
Is unsuitable for IHC-P.
May play a role in spermatogenesis or folliculogenesis.
Contains 2 bromo domains.
Contains 1 ET domain.
One bromodomain is sufficient for a partial interaction with histone H4 acetylated at 'Lys-13'.
Information by UniProt
BRD 2 antibody
This product has been referenced in:
et al. Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes. Oncotarget 7:79637-79653 (2016).
Read more (PubMed: 27793034) »
et al. BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells. Oncotarget 6:17698-712 (2015).
Read more (PubMed: 25989842) »
See all 4 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"