概述

  • 产品名称Anti-BRCC2抗体
  • 描述
    小鼠单克隆抗体to BRCC2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 2-109 of Human BRCC2

性能

应用

Our Abpromise guarantee covers the use of ab57813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Functions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death.
    • 组织特异性Ubiquitously expressed.
    • 细胞定位Cytoplasm. Mitochondrion. Lower abundance in mitochondrion than in cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BH3-like motif containing, cell death inducer antibody
      • BH3-like motif-containing cell death inducer antibody
      • BLID antibody
      • BLID_HUMAN antibody
      • BRCC2 antibody
      • breast cancer cell 2 antibody
      • Breast cancer cell protein 2 antibody
      see all

    Anti-BRCC2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57813 BRCC2 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    Anti-BRCC2 antibody (ab57813)参考文献

    This product has been referenced in:
    • Li X  et al. BRCC2 inhibits breast cancer cell growth and metastasis in vitro and in vivo via downregulating AKT pathway. Cell Death Dis 4:e757 (2013). Read more (PubMed: 23928696) »

    See 1 Publication for this product

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