产品名称 Anti-BPGM抗体 参阅全部 BPGM 一抗
WB, ICC/IF more details
Mouse, Rat, Rabbit, Cow
Recombinant fragment containing a sequence corresponding to a region within amino acids 1-216 of Human BPGM (NP_001715).
293T, A431 and H1299 whole cell lysates; HeLa cells; HeLaS3, Molt-4 and Raji cell lines
存放说明 Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
纯度 Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 30 kDa.
1/100 - 1/200.
功能 Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 18.104.22.168) and phosphatase (EC 22.214.171.124) activities.
疾病相关 Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) [MIM:222800]. A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.
序列相似性 Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
翻译后修饰 Glycation of Lys-159 in diabetic patients inactivates the enzyme.
Information by UniProt
2,3-bisphosphoglycerate mutase antibody
2,3-bisphosphoglycerate mutase, erythrocyte antibody
Anti-BPGM antibody 图像
Western blot - BPGM antibody (ab97497)
All lanes : Anti-BPGM antibody (ab97497) at 1/1000 dilution Lane 1 : 293T whole cell lysate Lane 2 : A431 whole cell lysate Lane 3 : H1299 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size : 30 kDa
Immunocytochemistry/ Immunofluorescence - BPGM antibody (ab97497)
ab97497, at 1/100 dilution, staining BPGM in paraformaldehyde-fixed HeLa cells by Immunofluorescence. Lower image is merged with DNA probe.
Anti-BPGM antibody (ab97497)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"