Anti-Bordetella pertussis toxin subunit S2抗体[20.6] (ab27158)

概述

  • 产品名称Anti-Bordetella pertussis toxin subunit S2抗体[20.6]
  • 描述
    小鼠单克隆抗体[20.6] to百日咳杆菌toxin subunit S2
  • 特异性Reacts with the intact toxin as well as the S2 subunit. Some reactivity towards the toxoid is also present.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    Reacts with Bordetella pertussis. Not yet tested in other species.
  • 免疫原

    Pertussis Toxin.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: None
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4.
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号20.6
  • 骨髓瘤x63-Ag8.653
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab27158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/100000.
WB 1/1000.

靶标

  • 相关性Pertussis toxin (islet activating protein) is the major protein toxin produced by virulent strains of Bordetella pertussis. As revealed by polyacrylamide gel electrophoresis, the purified protein consists of five dissimilar subunits: S1 (MW 28,000), S2 (MW 23,000), S3 (MW 22,000), S4 (MW 11,700) and S5 (MW 9,300), in a molar ratio of 1:1:1:2:1. The A protomer, S1 is responsible for the enzymatic activity of the toxin. Together, S2, S3, S4 and S5 comprise the B oligomer, responsible for binding the toxin to the cell surface.
  • 别名
    • B.pertussis S2 antibody
    • B.pertussis toxin subunit S2 antibody
    • Bordetella pertussis S2 antibody
    • IAP S2 antibody
    • Islet activating protein S2 antibody
    • Pertussis toxin S2 antibody
    • Pertussis toxin subunit 2 antibody
    • Ptx B antibody
    • PTX S2 antibody
    • PtxB antibody
    see all

Anti-Bordetella pertussis toxin subunit S2 antibody [20.6] (ab27158)参考文献

This product has been referenced in:
  • Ibsen PH The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine monoclonal antibodies. Vaccine 14:359-68 (1996). Read more (PubMed: 8735545) »
  • Ibsen PH The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine monoclonal antibodies. Vaccine 14:359-68 (1996). Read more (PubMed: 8735545) »

See all 2 Publications for this product

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