Anti-Bordetella pertussis抗体[BDI500] (ab24212)

概述

  • 产品名称Anti-Bordetella pertussis抗体[BDI500]
  • 描述
    小鼠单克隆抗体[BDI500] to百日咳杆菌
  • 特异性Specific for LOS-A of B. pertussis and B. bronchiseptica.
  • 经测试应用适用于: ELISA, ICC/IF, WBmore details
  • 种属反应性
    Reacts with Bordetella pertussis. Not yet tested in other species.
  • 免疫原

    Bordetella pertussis N-lauroyl sarcosine membrane extract.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明>90% pure.
  • 克隆单克隆
  • 克隆编号BDI500
  • 同种型IgG3
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab24212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
ICC/IF
WB
  • 应用说明ELISA: 1/20 - 1/200. IF: 1/10 - 1/50. WB: 1/10 - 1/50. Dilution optimised using Chromogenic detection.
  • 靶标

    • 相关性Bordetella pertussis is an aerobic, gram negative coccobacilli. It causes whooping cough (pertussis), an acute respiratory infection marked by severe, spasmodic coughing episodes during the paroxysmal phase. Leukocytosis with lymphocytosis is also common during this phase of the illness. Dangerous complications are bronchopneumonia and acute encephalopathy. It produces a number of virulence factors, including pertussis toxin, adenylate cyclase toxin, filamentous hemagglutinin, and hemolysin. Agglutinogens and other outer membrane proteins are important antigens. Pertussis toxin (islet activating protein) is the major protein toxin produced by virulent strains of Bordetella pertussis. As revealed by polyacrylamide gel electrophoresis, the purified protein consists of five dissimilar subunits: S1 (MW 28,000), S2 (MW 23,000), S3 (MW 22,000), S4 (MW 11,700) and S5 (MW 9,300), in a molar ratio of 1:1:1:2:1. The A protomer, S1 is responsible for the enzymatic activity of the toxin. Together, S2, S3, S4 and S5 comprise the B oligomer, responsible for binding the toxin to the cell surface.
    • 别名
      • B.pertussis antibody

    Anti-Bordetella pertussis antibody [BDI500] (ab24212)参考文献

    ab24212 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. We have one antibody raised against B. pertussis but it has not been tested in IHC on paraffin-embedded tissue. It may work in this application, but our guarantee does not cover IHC. Here is a link to the dat...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"