Anti-BOB1抗体[Wue-AC5] (ab31834)

概述

  • 产品名称Anti-BOB1抗体[Wue-AC5]
    参阅全部 BOB1 一抗
  • 描述
    小鼠单克隆抗体[Wue-AC5] to BOB1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A recombinant BOB1 protein from C terminal domain (Human).

  • 阳性对照
    • Tonsil.

性能

应用

Our Abpromise guarantee covers the use of ab31834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/50 - 1/100 for 30 minutes at room temperature when using ABC method. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. In particular, perform high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
    • 组织特异性B-cell specific.
    • 疾病相关Note=A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.
    • 序列相似性Belongs to the POU2AF1 family.
    • 翻译后修饰Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B cell Oct binding protein 1 antibody
      • B cell specific coactivator OBF 1 antibody
      • B cell specific coactivator OBF1 antibody
      • B-cell-specific coactivator OBF-1 antibody
      • BOB 1 antibody
      • BOB-1 antibody
      • OBF 1 antibody
      • OBF1 antibody
      • OBF1_HUMAN antibody
      • OCA B antibody
      • OCA-B antibody
      • OCAB antibody
      • OCT binding factor 1 antibody
      • OCT-binding factor 1 antibody
      • POU class 2 associating factor 1 antibody
      • POU domain class 2 associating factor 1 antibody
      • POU domain class 2-associating factor 1 antibody
      • Pou2af1 antibody
      see all

    Anti-BOB1 antibody [Wue-AC5] (ab31834)参考文献

    ab31834 has not yet been referenced specifically in any publications.

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