Anti-BOB1抗体, prediluted (ab52136)

概述

  • 产品名称Anti-BOB1抗体, prediluted
    参阅全部 BOB1 一抗
  • 描述
    兔多克隆抗体to BOB1, prediluted
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    A synthetic peptide from the C-terminus of human Bob1

  • 阳性对照
    • Raji cells and human tonsil.

性能

应用

Our Abpromise guarantee covers the use of ab52136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
WB 1/1.

靶标

  • 功能Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
  • 组织特异性B-cell specific.
  • 疾病相关Note=A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.
  • 序列相似性Belongs to the POU2AF1 family.
  • 翻译后修饰Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B cell Oct binding protein 1 antibody
    • B cell specific coactivator OBF 1 antibody
    • B cell specific coactivator OBF1 antibody
    • B-cell-specific coactivator OBF-1 antibody
    • BOB 1 antibody
    • BOB-1 antibody
    • OBF 1 antibody
    • OBF1 antibody
    • OBF1_HUMAN antibody
    • OCA B antibody
    • OCA-B antibody
    • OCAB antibody
    • OCT binding factor 1 antibody
    • OCT-binding factor 1 antibody
    • POU class 2 associating factor 1 antibody
    • POU domain class 2 associating factor 1 antibody
    • POU domain class 2-associating factor 1 antibody
    • Pou2af1 antibody
    see all

Anti-BOB1 antibody, prediluted 图像

  • ab52136, ready to use for staining human BOB1 in tonsil tissue by Immunohistochemistry, Formalin fixed Paraffin embedded tissue.
  • Anti-BOB1 antibody (ab52103) at 1/25 dilution + lysate prepared from Ramos cells

    Observed band size : 35 kDa (why is the actual band size different from the predicted?)

Anti-BOB1 antibody, prediluted (ab52136)参考文献

ab52136 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"