概述

  • 产品名称Anti-BNP抗体
    参阅全部 BNP 一抗
  • 描述
    兔多克隆抗体to BNP
  • 特异性Cross-reactivity to other pepertides: Human Atrial Natriuretic Peptide 0% Rat Atrial Natriuretic Peptide 0% ACTH (human, 1-39) 0% Vasoactive Intestinal Peptide (VIP) 0%
  • 经测试应用适用于: IHC-P, ELISA, RIA, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human) conjugated to bovine thyroglobulin.

性能

应用

Our Abpromise guarantee covers the use of ab19646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
RIA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

靶标

  • 相关性Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • BNP(1-28) antibody
    • BNP(1-29) antibody
    • BNP(1-30) antibody
    • BNP(1-32) antibody
    • BNP(2-31) antibody
    • BNP(3-29) antibody
    • BNP(3-30) antibody
    • BNP(3-32) antibody
    • BNP(4-27) antibody
    • BNP(4-29) antibody
    • BNP(4-30) antibody
    • BNP(4-31) antibody
    • BNP(4-32) antibody
    • BNP(5-29) antibody
    • BNP(5-31) antibody
    • BNP(5-32) antibody
    • Brain natriuretic peptide 32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Natriuretic peptide B antibody
    • Natriuretic peptide precursor B antibody
    • natriuretic peptide, brain type antibody
    • Natriuretic peptides B antibody
    • natriuretic protein antibody
    • NPPB antibody
    see all

Anti-BNP antibody (ab19646)参考文献

This product has been referenced in:

See 1 Publication for this product

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (iCell® Cardiomyocytes)
Permeabilization No
Specification iCell® Cardiomyocytes
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative Acetone
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Verified customer

提交于 Aug 31 2015

Application Flow Cytometry
Fixation Acetone
Permeabilization No
Sample Human Cell (iCell­ Cardiomyocytes)
Specification iCell­ Cardiomyocytes
Gating Strategy negative control cells
Preparation Cell harvesting/tissue preparation method: 1 mM EDTA/1 mM EGTA in PBS (calcium- and magnesium-free)
Sample buffer: DPBS
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Verified customer

提交于 Feb 13 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"