概述

  • 产品名称
  • 描述
    兔多克隆抗体to BNP
  • 特异性
    ab14358 recognises synthetic BNP.
  • 经测试应用
    适用于: RIAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Poly Lysin conjgated synthetic peptide:

    SPKMVQGSGC(G)

    , corresponding to amino acids 1-10 of Human BNP.

性能

应用

Our Abpromise guarantee covers the use of ab14358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
RIA 1/500.

靶标

  • 相关性
    Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
  • 细胞定位
    Secreted
  • 数据库链接
  • 别名
    • BNP(1-28) antibody
    • BNP(1-29) antibody
    • BNP(1-30) antibody
    • BNP(1-32) antibody
    • BNP(2-31) antibody
    • BNP(3-29) antibody
    • BNP(3-30) antibody
    • BNP(3-32) antibody
    • BNP(4-27) antibody
    • BNP(4-29) antibody
    • BNP(4-30) antibody
    • BNP(4-31) antibody
    • BNP(4-32) antibody
    • BNP(5-29) antibody
    • BNP(5-31) antibody
    • BNP(5-32) antibody
    • Brain natriuretic peptide 32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Natriuretic peptide B antibody
    • Natriuretic peptide precursor B antibody
    • natriuretic peptide, brain type antibody
    • Natriuretic peptides B antibody
    • natriuretic protein antibody
    • NPPB antibody
    see all

文献

ab14358 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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