Anti-BNP抗体[26E2] (HRP) (ab14701)

概述

  • 产品名称
    Anti-BNP抗体[26E2] (HRP)
    参阅全部 BNP 一抗
  • 描述
    小鼠单克隆抗体[26E2] to BNP (HRP)
  • 偶联物
    HRP
  • 经测试应用
    适用于: WB, Sandwich ELISA, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide: SPKMVQGSGC FGRKMDRIS S SSGLGCKV LR RH, corresponding to the last 32 amino acids of the 134 aa preproBNP sequence that is listed in Swissprot

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

应用

Our Abpromise guarantee covers the use of ab14701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent dilution. Detection
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [50E1] to BNP (ab20984).

靶标

  • 相关性
    Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
  • 细胞定位
    Secreted
  • 数据库链接
  • 别名
    • BNP(1-28) antibody
    • BNP(1-29) antibody
    • BNP(1-30) antibody
    • BNP(1-32) antibody
    • BNP(2-31) antibody
    • BNP(3-29) antibody
    • BNP(3-30) antibody
    • BNP(3-32) antibody
    • BNP(4-27) antibody
    • BNP(4-29) antibody
    • BNP(4-30) antibody
    • BNP(4-31) antibody
    • BNP(4-32) antibody
    • BNP(5-29) antibody
    • BNP(5-31) antibody
    • BNP(5-32) antibody
    • Brain natriuretic peptide 32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Natriuretic peptide B antibody
    • Natriuretic peptide precursor B antibody
    • natriuretic peptide, brain type antibody
    • Natriuretic peptides B antibody
    • natriuretic protein antibody
    • NPPB antibody
    see all

实验方案

文献

ab14701 has not yet been referenced specifically in any publications.

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