Anti-BNIP3抗体[ANa40] (ab10433)

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ab10433 被引用在 56 文献中.

  • Ono M  et al. Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1a Protein Replacement Human Cell Lines. PLoS One 11:e0154759 (2016). ICC/IF ; Human . PubMed: 27128805
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  • Deguise MO  et al. Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy. Sci Rep 6:28846 (2016). WB ; Mouse . PubMed: 27349908
  • Ortmann B  et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci 129:191-205 (2016). PubMed: 26644182
  • Malherbe JA  et al. Megakaryocytic hyperplasia in myeloproliferative neoplasms is driven by disordered proliferative, apoptotic and epigenetic mechanisms. J Clin Pathol 69:155-63 (2016). IHC-P ; Human . PubMed: 26290261
  • Zhang S  et al. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Oncotarget 6:43508-28 (2015). WB . PubMed: 26496038
  • Seillier M  et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18 (2015). WB . PubMed: 25828351
  • Wu HM  et al. Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells. Sci Rep 5:12291 (2015). WB ; Human . PubMed: 26201611
  • Moniz S  et al. Cezanne regulates E2F1-dependent HIF2a expression. J Cell Sci 128:3082-93 (2015). WB ; Human . PubMed: 26148512
  • Zhang X  et al. Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments. Nat Commun 5:3295 (2014). WB . PubMed: 24548894
  • Kim JY  et al. Expression of autophagy-related proteins according to androgen receptor and HER-2 status in estrogen receptor-negative breast cancer. PLoS One 9:e105666 (2014). IHC-P ; Human . PubMed: 25140630
  • Ni HM  et al. Role of hypoxia inducing factor-1ß in alcohol-induced autophagy, steatosis and liver injury in mice. PLoS One 9:e115849 (2014). Mouse . PubMed: 25536043
  • Choi J  et al. Metabolic interaction between cancer cells and stromal cells according to breast cancer molecular subtype. Breast Cancer Res 15:R78 (2013). PubMed: 24020991
  • Van Beersel G  et al. Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts. Biosci Rep 33:e00023 (2013). WB . PubMed: 23249249
  • Sanchez-Alvarez R  et al. Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin. Cell Cycle 12:172-82 (2013). PubMed: 23257779
  • Sanchez-Alvarez R  et al. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle 12:289-301 (2013). Human . PubMed: 23257780
  • Al-Zoubi M  et al. Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFa completely prevents breast cancer tumor formation in vivo. Cell Cycle 12:480-90 (2013). PubMed: 23292149
  • Avena P  et al. Compartment-specific activation of PPAR? governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle 12:1360-70 (2013). PubMed: 23574724
  • Lin A  et al. The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress. Oncogene N/A:N/A (2013). PubMed: 23851496
  • Ni HM  et al. Critical Role of FoxO3a in Alcohol-Induced Autophagy and Hepatotoxicity. Am J Pathol 183:1815-25 (2013). Mouse . PubMed: 24095927
  • Ma X  et al. Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death. Autophagy 8: (2012). WB, ICC/IF ; Rat . PubMed: 22302006
  • Capparelli C  et al. CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis. Cell Cycle 11:3599-610 (2012). PubMed: 22935696
  • Jin T  et al. Expression TGM2 and BNIP3 have prognostic significance in laryngeal cancer patients receiving surgery and postoperative radiotherapy: a retrospective study. J Transl Med 10:64 (2012). IHC-P ; Human . PubMed: 22458929
  • Capparelli C  et al. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle 11:2285-302 (2012). PubMed: 22684298
  • Capparelli C  et al. CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth. Cell Cycle 11:2272-84 (2012). PubMed: 22684333
  • Salem AF  et al. Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells. Cell Cycle 11:2545-56 (2012). PubMed: 22722266
  • Guido C  et al. Metabolic reprogramming of cancer-associated fibroblasts by TGF-ß drives tumor growth: connecting TGF-ß signaling with "Warburg-like" cancer metabolism and L-lactate production. Cell Cycle 11:3019-35 (2012). WB, ICC/IF ; Human . PubMed: 22874531
  • Guido C  et al. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth. Oncotarget 3:798-810 (2012). WB ; Human . PubMed: 22878233
  • Carito V  et al. Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth. Cell Cycle 11:3403-14 (2012). Human . PubMed: 22918248
  • Salem AF  et al. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1a, autophagy and ketone body production. Cell Cycle 11:4167-73 (2012). PubMed: 23047605
  • An HJ  et al. Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway. Mol Cells 31:579-83 (2011). WB ; Human . PubMed: 21573703
  • Feng X  et al. p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death. EMBO J 30:3397-415 (2011). WB ; Human . PubMed: 21792176
  • An HJ  et al. The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation. Biochim Biophys Acta 1813:2088-98 (2011). WB ; Mouse . PubMed: 21856340
  • Zois CE  et al. "Autophagic flux" in normal mouse tissues: focus on endogenous LC3A processing. Autophagy 7:1371-8 (2011). PubMed: 21997374
  • Chiavarina B  et al. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth. Cancer Biol Ther 12: (2011). Human . PubMed: 22236875
  • Wu SY  et al. Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation. Neoplasia 13:1171-82 (2011). WB ; Mouse . PubMed: 22241963
  • Xu P  et al. JNK regulates FoxO-dependent autophagy in neurons. Genes Dev 25:310-22 (2011). WB ; Mouse . PubMed: 21325132
  • Zois CE  et al. Lung autophagic response following exposure of mice to whole body irradiation, with and without amifostine. Biochem Biophys Res Commun 404:552-8 (2011). WB ; Mouse . PubMed: 21145309
  • Melvin A  et al. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH. Mol Biol Cell 22:4171-81 (2011). PubMed: 21900490
  • Ameri K  et al. Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype. Br J Cancer 102:561-9 (2010). WB ; Human . PubMed: 20051957
  • Newton IP  et al. Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection. Mol Biol Cell 21:3630-8 (2010). PubMed: 20844082
  • Martinez-Outschoorn UE  et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF?B activation in the tumor stromal microenvironment. Cell Cycle 9:3515-33 (2010). PubMed: 20855962
  • Pavlides S  et al. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism. Cell Cycle 9:3485-505 (2010). WB ; Mouse . PubMed: 20861672
  • Chiavarina B  et al. HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis. Cell Cycle 9:3534-51 (2010). ICC/IF ; Human . PubMed: 20864819
  • Bellot G  et al. Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol 29:2570-81 (2009). WB ; Mouse . PubMed: 19273585
  • Cleven AH  et al. Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis. Br J Cancer 99:727-33 (2008). IHC-P ; Human . PubMed: 18728663
  • Zhang H  et al. Mitochondrial autophagy is a HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem : (2008). WB ; Human . PubMed: 18281291
  • Valdez BC  et al. Altered gene expression in busulfan-resistant human myeloid leukemia. Leuk Res 32:1684-97 (2008). PubMed: 18339423
  • Hetschko H  et al. BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells. Neoplasia 10:873-85 (2008). WB ; Human . PubMed: 18670645
  • Pisano C  et al. Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968. Eur J Cancer 44:1332-40 (2008). WB ; Human . PubMed: 18445521
  • Lee SH  et al. Mutational and expressional analysis of BNIP3, a pro-apoptotic Bcl-2 member, in gastric carcinomas. APMIS 115:1274-80 (2007). PubMed: 18092960
  • Diwan A  et al. Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice. J Clin Invest 117:2825-33 (2007). WB ; Mouse . PubMed: 17909626
  • Tracy K  et al. BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol Cell Biol 27:6229-42 (2007). WB, ICC/IF ; Mouse . PubMed: 17576813
  • An HJ  et al. Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death. J Biol Chem 281:33939-48 (2006). PubMed: 16954213
  • Murai M  et al. Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours. Br J Cancer 92:1165-72 (2005). PubMed: 15756280

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