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概述

  • 产品名称Anti-BMP9抗体
    参阅全部 BMP9 一抗
  • 描述
    兔多克隆抗体to BMP9
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide from the N-terminal region of human BMP9 conjugated to KLH

  • 阳性对照
    • Mouse liver tissue lysate and human hepatocellular carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab71809 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).
IHC-P 1/50 - 1/100.
ELISA 1/1000.

靶标

  • 相关性BMP9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. They are regulators of cell growth and differentiation. BMP9 has a role in the maturation of BFCN (basal forebrain cholinergic neurons) also inducing and maintaining the ability of these cells to respond to acetylcholine; BFCN are important for the processes of learning, memory and attention. BMP9 is a potent inducer of hepcidin (a cationic peptide that has a antimicrobial properties) in hepatocytes and can regulate iron metabolism. The physiological receptor of BMP9 is thought to be activin receptor-like kinase 1, ALK1 (also called ACVRL1), an endothelial-specific type I receptor of the TGF-beta receptor family. BMP9 is one of the most potent BMPs to induce orthotopic bone formation in vivo. BMP3, a blocker of most BMPs seems not to affect BMP9.
  • 细胞定位Secreted
  • 数据库链接
    • 别名
      • BMP 9 antibody
      • Bone morphogenetic protein 9 antibody
      • GDF 2 antibody
      • GDF2 antibody
      • growth differentiation factor 2 antibody
      • Growth/differentiation factor 2 antibody
      • HHT5 antibody
      see all

    Anti-BMP9 antibody 图像

    • Western blot - BMP9 antibody (ab71809)
      Western blot - BMP9 antibody (ab71809)
      Anti-BMP9 antibody (ab71809) at 1/100 dilution + mouse liver tissue lysate at 12.5 µg

      Predicted band size : 47 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - BMP9 antibody (ab71809)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - BMP9 antibody (ab71809)
      ab71809 at 1/50 dilution, staining BMP9 in human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

    Anti-BMP9 antibody (ab71809)参考文献

    ab71809 has not yet been referenced specifically in any publications.

    发表研究结果有使用 ab71809？请让我们知道，以便我们可以引用本数据表中的参考文章。

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