概述

  • 产品名称
  • 描述
    兔多克隆抗体to BMP7
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Chicken, Human
  • 免疫原

    Synthetic peptide corresponding to Human BMP7 (C terminal).
    Database link: NM_001719

  • 阳性对照
    • Rat kidney tissue; Human kidney cell lysate

应用

Our Abpromise guarantee covers the use of ab93636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明
    IHC-P: 1/50 - 1/200.
    WB: 1/200 - 1/1000. Predicted molecular weight: 49 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
    • 组织特异性
      Expressed in the kidney and bladder. Lower levels seen in the brain.
    • 序列相似性
      Belongs to the TGF-beta family.
    • 发展阶段
      Expressed in the developing eye, brain and ear during embryogenesis.
    • 翻译后修饰
      Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BMP 7 antibody
      • BMP-7 antibody
      • Bmp7 antibody
      • BMP7_HUMAN antibody
      • Bone morphogenetic protein 7 antibody
      • Bone morphogenic protein 7 antibody
      • Eptotermin alfa antibody
      • OP 1 antibody
      • OP-1 antibody
      • OP1 antibody
      • Osteogenic protein 1 antibody
      see all

    图片

    • ab93636, at 1/100 dilution, staining secreted BMP7 in formalin-fixed, paraffin-embedded rat kidney tissue by Immunohistochemistry.
    • Anti-BMP7 antibody (ab93636) at 1/200 dilution + Human kidney cell lysate

      Predicted band size : 49 kDa

    文献

    This product has been referenced in:
    • Zhang Y  et al. Effects of imposed defocus of opposite sign on temporal gene expression patterns of BMP4 and BMP7 in chick RPE. Exp Eye Res 109:98-106 (2013). Read more (PubMed: 23428741) »

    See 1 Publication for this product

    客户评价及客户问答

    Thank you for contacting us.

    The lab let me know that this antibody was raised against a peptide from near the C terminal residues of human BMP-7 protein (within residues 200-400).

    I hope this information is helpful to you. Please...

    Read More
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Chicken Tissue lysate - whole (retina, RPE, choroid)
    Loading amount
    20 µg
    Specification
    retina, RPE, choroid
    Gel Running Conditions
    Reduced Denaturing (NuPAGE 4-12% Bis-Tris Gel)
    Blocking step
    (agent) for 30 minute(s) · Concentration: 100% · Temperature: 25°C
    Username

    Yan Zhang

    Verified customer

    提交于 Feb 28 2012

    Thank you for contacting Abcam. As you have requested, I have changed the status of your abreviews for ab6285 (abreview xxxx) and ab93939 (abreview xxxx) to an editing stage. This way you will be able to go back into those and change the information...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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