Anti-Blood Group H1 (O) antigen抗体[17-206] (ab3355)

概述

  • 产品名称Anti-Blood Group H1 (O) antigen抗体[17-206]
  • 描述
    小鼠单克隆抗体[17-206] to Blood Group H1 (O) antigen
  • 特异性Blood Group Antigen H (O) Type 1 (BG4). This antibody does not cross-react with the H blood group substance of the Type 2 backbone.
  • 经测试应用适用于: IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    SW-403 Colon Cancer Cell Line (Human).

  • 阳性对照
    • Kidney or antrum (human).

性能

应用

Our Abpromise guarantee covers the use of ab3355 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. Antigen retrieval is not essential but may optimise staining.
ELISA Use at an assay dependent concentration. PubMed: 24096735

靶标

  • 相关性Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood Group H1 (O) is one of a series of well characterised murine monoclonal antibodies detecting blood group specificities of the ABH and Lewis systems. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
  • 数据库链接

Anti-Blood Group H1 (O) antigen antibody [17-206] 图像

Anti-Blood Group H1 (O) antigen antibody [17-206] (ab3355)参考文献

This product has been referenced in:
  • Radziejewska I  et al. Influence of monoclonal anti-Lewis b, anti-H type 1, and anti-sialyl Lewis x antibodies on binding of Helicobacter pylori to MUC1 mucin. Mol Cell Biochem 385:249-55 (2014). Sandwich ELISA ; Human . Read more (PubMed: 24096735) »
  • Gao C  et al. Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a Mucin O-Glycome Designer Array. J Biol Chem 289:16462-77 (2014). Read more (PubMed: 24753245) »

See all 6 Publications for this product

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To our knowledge, ab3355 has not been tested in WB. However by participating in our AbTrial program you can now use our products in an untested application or species without financial risk...

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We have been having a very difficult time searching for the original publication on this clone. These clones are very old (˜1980's) and a lot of the publications reference different nomenc...

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Indeed this antibody is an Ascite. The antibody concentration is therefore not known. We do however estimate that an average ascite hasa concentrationfrom 1 to 10 mg/ml, with about 90% of specific antibodies.
...

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