Anti-Blood Group A Antigen抗体[9A] (ab20131)

概述

  • 产品名称Anti-Blood Group A Antigen抗体[9A]
    参阅全部 Blood Group A Antigen 一抗
  • 描述
    小鼠单克隆抗体[9A] to Blood Group A Antigen
  • 特异性 ab20131 cross reacts with EGF receptor in A431 cells only due to glycosylation defects in these cells which reveals otherwise cryptic sugar structures.
  • 经测试应用适用于: ELISA, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Cell preparation: A431 cells (human vulval squamous carcinoma cell line).

性能

应用

Our Abpromise guarantee covers the use of ab20131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

靶标

  • 相关性Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
  • 细胞定位Cell Membrane
  • 数据库链接

Anti-Blood Group A Antigen antibody [9A] (ab20131)参考文献

This product has been referenced in:
  • Gullick WJ & Lemoine NR 'EGF receptor' antibody 29.1.1. J Pathol 162:275-6 (1990). Read more (PubMed: 2266467) »
  • Parker PJ  et al. Monoclonal antibodies against the human epidermal growth factor receptor from A431 cells. Isolation, characterization, and use in the purification of active epidermal growth factor receptor. J Biol Chem 259:9906-12 (1984). Read more (PubMed: 6086658) »

See all 2 Publications for this product

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"