Anti-BLK抗体(ab54866)

概述

  • 产品名称Anti-BLK抗体
    参阅全部 BLK 一抗
  • 描述
    小鼠单克隆抗体to BLK
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment: MGLVSSKKPD KEKPIKEKDK GQWSPLKVSA QDKDAPPLPP LVVFNHLTPP PPDEHLDEDK HFVVALYDYT AMNDRDLQML KGEKLQVLKG , corresponding to amino acids 1-90 of Human BLK

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab54866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Modulator of beta-cells function, acting through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose.
    • 组织特异性Expressed in lymphatic organs, pancreatic islets, Leydig cells, striate ducts of salivary glands and hair follicles.
    • 疾病相关Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11) [MIM:613375]. MODY11 is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.
    • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
      Contains 1 protein kinase domain.
      Contains 1 SH2 domain.
      Contains 1 SH3 domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B lymphocyte kinase antibody
      • B lymphoid tyrosine kinase antibody
      • Blk antibody
      • BLK nonreceptor tyrosine kinase antibody
      • BLK_HUMAN antibody
      • EC 2.7.10.2 antibody
      • MGC 10442 antibody
      • MGC10442 antibody
      • MODY 11 antibody
      • MODY11 antibody
      • P55 BLK antibody
      • p55-BLK antibody
      • Tyrosine kinase B lymphocyte specific antibody
      • Tyrosine protein kinase antibody
      • Tyrosine-protein kinase BLK antibody
      see all

    Anti-BLK antibody 图像



    • Predicted band size : 58 kDa
      BLK antibody (ab54866) at 1ug/lane + Raw cell lysate at 25ug/lane.

    Anti-BLK antibody (ab54866)参考文献

    ab54866 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your inquiry and I apologize for the delay in this reply as I was awaiting more information from the lab.   We don't have cross-reactivity data for ab54866. It has not been tested for cross-reactivity to Lck, Fyn, Lyn or any other Src ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"