概述

  • 产品名称
  • 描述
    兔多克隆抗体to BLAP75
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 275 and 300 of human BLAP75 (NP_079221.1)

  • 阳性对照
    • Human skin basal cell carcinoma tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab84387 was affinity purified using an epitope specific to BLAP75 immobilized on solid support.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
    • 序列相似性
      Belongs to the RMI1 family.
    • 细胞定位
      Nucleus. Forms foci in response to DNA damage.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BLAP75 antibody
      • BLM associated polypeptide 75 kDa antibody
      • BLM associated protein 75 kDa antibody
      • BLM-associated protein of 75 kDa antibody
      • C9orf76 antibody
      • FAAP75 antibody
      • FLJ12888 antibody
      • Homolog of yeast RecQ mediated genome instability 1 antibody
      • RecQ mediated genome instability 1 antibody
      • RecQ-mediated genome instability protein 1 antibody
      • Rmi1 antibody
      • RMI1 homolog antibody
      • RMI1 RecQ mediated genome instability 1 homolog antibody
      • RMI1_HUMAN antibody
      • RP11-346I8 antibody
      see all

    图片

    • ab84387, at 1/250 dilution, staining BLAP75 in formalin fixed, paraffin embedded human skin basal cell carcinoma tissue by Immunohistochemistry.
      Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1/100.

    文献

    ab84387 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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