Anti-Bile Acid Receptor NR1H4抗体(ab86025)

概述

  • 产品名称Anti-Bile Acid Receptor NR1H4抗体
    参阅全部 Bile Acid Receptor NR1H4 一抗
  • 描述
    兔多克隆抗体to Bile Acid Receptor NR1H4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Three synthetic peptides (human) conjugated to KLH

  • 阳性对照
    • An induced culture of E. coli

性能

应用

Our Abpromise guarantee covers the use of ab86025 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 56 kDa). Tag is 14kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
    • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BAR antibody
      • Bile acid receptor antibody
      • Farnesoid X activated receptor antibody
      • Farnesoid X receptor antibody
      • Farnesoid X-activated receptor antibody
      • Farnesol receptor HRR 1 antibody
      • Farnesol receptor HRR-1 antibody
      • Farnesol receptor HRR1 antibody
      • FXR antibody
      • HRR 1 antibody
      • HRR1 antibody
      • NR1H4 antibody
      • NR1H4_HUMAN antibody
      • Nuclear receptor subfamily 1 group H member 4 antibody
      • Retinoid X receptor interacting protein 14 antibody
      • Retinoid X receptor-interacting protein 14 antibody
      • RIP 14 antibody
      • RIP14 antibody
      • RXR interacting protein 14 antibody
      • RXR-interacting protein 14 antibody
      see all

    Anti-Bile Acid Receptor NR1H4 antibody 图像

    • All lanes : Anti-Bile Acid Receptor NR1H4 antibody (ab86025) at 1/1000 dilution

      Lane 1 : An un-induced culture of E. coli
      Lane 2 : An induced culture of E. coli

      Lysates/proteins at 1/5000 dilution per lane.

      Secondary
      Anti-Rabbit IgG HRP at 1/1000 dilution

      Predicted band size : 56 kDa
      Observed band size : 45,70 kDa (why is the actual band size different from the predicted?)


      Exposure time : 60 minutes

    Anti-Bile Acid Receptor NR1H4 antibody (ab86025)参考文献

    ab86025 has not yet been referenced specifically in any publications.

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