Anti-Bik抗体- Aminoterminal end (ab62494)

概述

  • 产品名称Anti-Bik抗体- Aminoterminal end
    参阅全部 Bik 一抗
  • 描述
    兔多克隆抗体to Bik - Aminoterminal end
  • 特异性This antibody reacts with Bik
  • 经测试应用适用于: WB, ICC, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A 15 amino acid synthetic peptide from near the amino terminus of human Bik

  • 阳性对照
    • Jurkat cell lysate and Jurkat cells

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab62494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 18 kDa).
ICC Use a concentration of 1 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.

靶标

  • 功能Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
  • 结构域Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
  • 细胞定位Endomembrane system. Around the nuclear envelope, and in cytoplasmic membranes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptosis inducer NBK antibody
    • BBC1 antibody
    • Bcl-2-interacting killer antibody
    • BCL2 interacting killer antibody
    • bhikhari antibody
    • BIK antibody
    • Bik-like killer protein antibody
    • BIK_HUMAN antibody
    • BIP 1 antibody
    • BiP1 antibody
    • BP 4 antibody
    • BP4 antibody
    • cb 60 antibody
    • NBK antibody
    see all

Anti-Bik antibody - Aminoterminal end 图像

  • Lane 1 : Anti-Bik antibody - Aminoterminal end (ab62494) at 1 µg/ml
    Lane 2 : Anti-Bik antibody - Aminoterminal end (ab62494) at 2 µg/ml

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 18 kDa
    Observed band size : 22 kDa (why is the actual band size different from the predicted?)
  • Immunocytochemistry of Bik in Jurkat cells with ab62494 antibody at 1 µg/ml.
  • Immunofluorescence of Bik in Jurkat cells using ab62494 at 10 ug/ml.

Anti-Bik antibody - Aminoterminal end (ab62494)参考文献

ab62494 has not yet been referenced specifically in any publications.

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