概述

  • 产品名称Anti-Bik抗体
    参阅全部 Bik 一抗
  • 描述
    小鼠单克隆抗体to Bik
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human, Recombinant Fragment
  • 免疫原

    Recombinant fragment: EDLDPMEDFD SLECMEGSDA LALRLACIGD EMDVSLRAPR LAQLSEVAMH SLGLAFIYDQ TEDIRDVLRS FMDGFTTLKE NIMRFWRSPN PGSWVSCEQV , corresponding to amino acids 37-136 of Human Bik

性能

应用

Our Abpromise guarantee covers the use of ab54862 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
    • 结构域Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
    • 细胞定位Endomembrane system. Around the nuclear envelope, and in cytoplasmic membranes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Apoptosis inducer NBK antibody
      • BBC1 antibody
      • Bcl-2-interacting killer antibody
      • BCL2 interacting killer antibody
      • bhikhari antibody
      • BIK antibody
      • Bik-like killer protein antibody
      • BIK_HUMAN antibody
      • BIP 1 antibody
      • BiP1 antibody
      • BP 4 antibody
      • BP4 antibody
      • cb 60 antibody
      • NBK antibody
      see all

    Anti-Bik antibody 图像

    • Bik antibody (ab54862) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.
    • Western blot against tagged recombinant protein immunogen using ab54862 Bik antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    Anti-Bik antibody (ab54862)参考文献

    ab54862 has not yet been referenced specifically in any publications.

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