概述

  • 产品名称Anti-BICD2抗体
    参阅全部 BICD2 一抗
  • 描述
    兔多克隆抗体to BICD2
  • 特异性this antibody does not cross react with BICD1.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to a 13 amino acid peptide from near the carboxy terminus of human BICD2.

  • 阳性对照
    • A549 cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab73286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa).

靶标

  • 功能May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the BicD family.
  • 结构域The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2.
  • 翻译后修饰Phosphorylated by NEK9 in vitro.
  • 细胞定位Golgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA526D8.1 antibody
    • Bic D 2 antibody
    • Bic-D 2 antibody
    • Bicaudal D homolog 2 (Drosophila) antibody
    • Bicaudal D homolog 2 antibody
    • Bicd2 antibody
    • BICD2_HUMAN antibody
    • Coiled coil protein BICD2 antibody
    • Cytoskeleton like bicaudal D protein homolog 2 antibody
    • Homolog of Drosophila bicaudal D antibody
    • KIAA0699 antibody
    • Protein bicaudal D homolog 2 antibody
    see all

Anti-BICD2 antibody 图像

  • Lane 1 : Anti-BICD2 antibody (ab73286) at 1 µg/ml
    Lane 2 : Anti-BICD2 antibody (ab73286) at 2 µg/ml

    Lane 1 : A549 cell lysate
    Lane 2 : A549 cell lysate

    Lysates/proteins at 15 µg/ml per lane.


    Predicted band size : 93 kDa
    Observed band size : 93 kDa

Anti-BICD2 antibody (ab73286)参考文献

ab73286 has not yet been referenced specifically in any publications.

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