概述

  • 产品名称Anti-BICD2抗体
    参阅全部 BICD2 一抗
  • 描述
    兔多克隆抗体to BICD2
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 625-675 of Human BICD2 (NP_056065.1).

  • 阳性对照
    • HeLa whole cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% Tris buffered saline
    Note: pH 7-8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab117799 was affinity purified using an epitope specific to BICD2 immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab117799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-10 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.
    • 组织特异性Ubiquitous.
    • 序列相似性Belongs to the BicD family.
    • 结构域The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2.
    • 翻译后修饰Phosphorylated by NEK9 in vitro.
    • 细胞定位Golgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology.
    • Information by UniProt
    • 数据库链接
    • 别名
      • bA526D8.1 antibody
      • Bic D 2 antibody
      • Bic-D 2 antibody
      • Bicaudal D homolog 2 (Drosophila) antibody
      • Bicaudal D homolog 2 antibody
      • Bicd2 antibody
      • BICD2_HUMAN antibody
      • Coiled coil protein BICD2 antibody
      • Cytoskeleton like bicaudal D protein homolog 2 antibody
      • Homolog of Drosophila bicaudal D antibody
      • KIAA0699 antibody
      • Protein bicaudal D homolog 2 antibody
      see all

    Anti-BICD2 antibody 图像

    • Lane 1: Staining of BICD2 in HeLa whole cell lysate immunoprecipitated using ab117799 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: control IgG. Predicted band size : 94 kDa. Exposure time: 30 seconds.

    Anti-BICD2 antibody (ab117799)参考文献

    ab117799 has not yet been referenced specifically in any publications.

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