Anti-MIST-1抗体[6E8/A12/C11P1] - C-terminal (ab110919)
Key features and details
- Mouse monoclonal [6E8/A12/C11P1] to MIST-1 - C-terminal
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
概述
-
产品名称
Anti-MIST-1抗体[6E8/A12/C11P1] - C-terminal
参阅全部 MIST-1 一抗 -
描述
小鼠单克隆抗体[6E8/A12/C11P1] to MIST-1 - C-terminal -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide corresponding to Mouse MIST-1 aa 175-197 (C terminal).
-
阳性对照
- Mouse pancreas tissue.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
-
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
6E8/A12/C11P1 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab110919于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/50.
|
说明 |
---|
IHC-P
1/50. |
靶标
-
功能
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. -
组织特异性
Expressed in brain, liver, spleen and skeletal muscle. -
序列相似性
Contains 1 basic helix-loop-helix (bHLH) domain. -
结构域
Lacks a classic transcription activation domain and instead possesses an N-terminal region capable of inhibiting heterologous activators. -
细胞定位
Nucleus. - Information by UniProt
-
数据库链接
- Entrez Gene: 17341 Mouse
- SwissProt: Q9QYC3 Mouse
- Unigene: 386767 Mouse
-
别名
- Basic helix loop helix domain containing class B 8 antibody
- Basic helix loop helix family member a15 antibody
- BHA15_HUMAN antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab110919 被引用在 1 文献中.
- Kim D et al. 3D Organoid Culture From Adult Salivary Gland Tissues as an ex vivo Modeling of Salivary Gland Morphogenesis. Front Cell Dev Biol 9:698292 (2021). PubMed: 34458260