Anti-beta Sarcoglycan抗体(ab83699)

概述

  • 产品名称Anti-beta Sarcoglycan抗体
    参阅全部 beta Sarcoglycan 一抗
  • 描述
    兔多克隆抗体to beta Sarcoglycan
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 180-229 (

    FSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNIKVDGRAIVRGN

    ) of Human beta Sarcoglycan (NP_000223)

  • 阳性对照
    • Human fetal heart lysate

性能

应用

Our Abpromise guarantee covers the use of ab83699 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/312500.

靶标

  • 功能Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • 组织特异性Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
  • 疾病相关Limb-girdle muscular dystrophy 2E
  • 序列相似性Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • 翻译后修饰Disulfide bonds are present.
  • 细胞定位Cell membrane, sarcolemma. Cytoplasm, cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 43 kDa dystrophin associated glycoprotein antibody
    • 43 kDa dystrophin-associated glycoprotein antibody
    • 43DAG antibody
    • A3b antibody
    • Beta SG antibody
    • Beta-sarcoglycan antibody
    • Beta-SG antibody
    • dystrophin-associated glycoprotein, 43-kD antibody
    • LGMD2E antibody
    • Limb girdle muscular dystrophy 2E (non linked families) antibody
    • Sarcoglycan beta antibody
    • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) antibody
    • SGC antibody
    • SGCB antibody
    • SGCB_HUMAN antibody
    see all

Anti-beta Sarcoglycan antibody 图像

  • Anti-beta Sarcoglycan antibody (ab83699) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)

Anti-beta Sarcoglycan antibody (ab83699)参考文献

ab83699 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab83699.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"