Anti-beta Sarcoglycan抗体(ab55683)


  • 产品名称Anti-beta Sarcoglycan抗体
    参阅全部 beta Sarcoglycan 一抗
  • 描述
    小鼠单克隆抗体to beta Sarcoglycan
  • 经测试应用适用于: WB, IHC-P, ELISA, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 87-197 of Human beta Sarcoglycan



Our Abpromise guarantee covers the use of ab55683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml.
IHC-P Use a concentration of 3 µg/ml.
ELISA Use at an assay dependent concentration.
Flow Cyt Use 0.5µg for 106 cells. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.


  • 功能Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • 组织特异性Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
  • 疾病相关Limb-girdle muscular dystrophy 2E
  • 序列相似性Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • 翻译后修饰Disulfide bonds are present.
  • 细胞定位Cell membrane, sarcolemma. Cytoplasm, cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 43 kDa dystrophin associated glycoprotein antibody
    • 43 kDa dystrophin-associated glycoprotein antibody
    • 43DAG antibody
    • A3b antibody
    • Beta SG antibody
    • Beta-sarcoglycan antibody
    • Beta-SG antibody
    • dystrophin-associated glycoprotein, 43-kD antibody
    • LGMD2E antibody
    • Limb girdle muscular dystrophy 2E (non linked families) antibody
    • Sarcoglycan beta antibody
    • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) antibody
    • SGC antibody
    • SGCB antibody
    • SGCB_HUMAN antibody
    see all

Anti-beta Sarcoglycan antibody 图像

  • beta Sarcoglycan antibody (ab55683) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human heart.
  • beta Sarcoglycan antibody (ab55683) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.
  • Overlay histogram showing A549 cells stained with ab55683 (red line). The cells were fixed with 80% methanol (5 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab55683, 0.5µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1µg/1x106 cells) used under the same conditions. Unlabelled sample (blue line). Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

    Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-beta Sarcoglycan antibody (ab55683)参考文献

ab55683 has not yet been referenced specifically in any publications.

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