Anti-beta Crystallin A3抗体(ab90171)


  • 产品名称Anti-beta Crystallin A3抗体
    参阅全部 beta Crystallin A3 一抗
  • 描述
    兔多克隆抗体to beta Crystallin A3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 2-51 (ETQAEQQELE TLPTTKMAQT NPTPGSLGPW KITIYDQENF QGKRMEFTSS) of Human beta Crystallin A3 (NP_005199).

  • 阳性对照
    • HT1080 cell lysate


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified by peptide affinity chromatography method.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab90171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • 功能Crystallins are the dominant structural components of the vertebrate eye lens.
  • 疾病相关Defects in CRYBA1 are the cause of cataract congenital zonular with sutural opacities (CCZS) [MIM:600881]. A form of zonular cataract. Zonular or lamellar cataracts are concentric opacities, broad or narrow, usually consisting of powdery white dots affecting one lamella or zonule of an otherwise clear lens.
  • 序列相似性Belongs to the beta/gamma-crystallin family.
    Contains 4 beta/gamma crystallin 'Greek key' domains.
  • 结构域Has a two-domain beta-structure, folded into four very similar Greek key motifs.
  • 翻译后修饰Specific cleavages in the N-terminal arm occur during lens maturation and give rise to several truncated forms. Cleavages do not seem to have adverse effects on solubility.
    S-methylation and glutathionylation occur in normal young lenses and do not seem to be detrimental.
    Isoform A1 initiator methionine is removed. The new N-terminal amino acid is then N-acetylated.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta crystallin A3 isoform A1 Delta4 form antibody
    • Beta crystallin A3 antibody
    • Beta crystallin A3 isoform A1 Delta7 form antibody
    • Beta crystallin A3 isoform A1 Delta8 form antibody
    • Beta-crystallin A3 antibody
    • CRBA1_HUMAN antibody
    • CRYB1 antibody
    • CRYBA1 antibody
    • Crystallin beta A1 antibody
    • Crystallin beta A3 antibody
    • Delta8 form antibody
    • Eye lens structural protein antibody
    • isoform A1 antibody
    see all

Anti-beta Crystallin A3 antibody 图像

  • Anti-beta Crystallin A3 antibody (ab90171) at 1 µg/ml (in 5% skim milk / PBS buffer) + HT1080 cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 25 kDa

Anti-beta Crystallin A3 antibody (ab90171)参考文献

ab90171 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Recombinant protein (lens)
Loading amount 1 µg
Specification lens
Gel Running Conditions Non-reduced Denaturing (10%)
Blocking step SuperBlock Blocking Buffer- Blotting in TBS as blocking agent for 30 minute(s) · Concentration: 100% · Temperature: 24°C

Leonel Trujillo

Verified customer

提交于 Apr 19 2010