概述
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产品名称Anti-beta 2 Microglobulin抗体- C-terminal
参阅全部 beta 2 Microglobulin 一抗 -
描述兔多克隆抗体to beta 2 Microglobulin - C-terminal
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经测试应用适用于: ELISA, IHC-Pmore details
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种属反应性与反应: Human
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免疫原
Synthetic peptide from the C terminal region of Human beta 2 Microglobulin, conjugated to KLH.
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阳性对照
- Human lung carcinoma tissue.
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.09% Sodium Azide
Constituents: PBS -
Concentration information loading... -
纯度Ammonium Sulphate Precipitation
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纯化说明Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab80071 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA | 1/1000. | |
| IHC-P | 1/10 - 1/50. |
靶标
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功能Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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疾病相关Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis. -
序列相似性Belongs to the beta-2-microglobulin family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
翻译后修饰Glycation of Ile-21 is observed in long-term hemodialysis patients.
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细胞定位Secreted. Detected in serum and urine.
- Information by UniProt
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数据库链接
- Entrez Gene: 567 Human
- Omim: 109700 Human
- SwissProt: P61769 Human
- Unigene: 534255 Human
- Unigene: 702947 Human
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别名
- B2M antibody
- B2MG_HUMAN antibody
- Beta 2 microglobin antibody
see all
Anti-beta 2 Microglobulin antibody - C-terminal 图像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - beta 2 Microglobulin antibody - C-terminal (ab80071)Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human lung carcinoma tissue using ab80068 at a 1/10 dilution, with a peroxidase-conjugated secondary antibody, followed by DAB staining. -
Western blot - beta 2 Microglobulin antibody - C-terminal (ab80071)All lanes : Anti-beta 2 Microglobulin antibody - C-terminal (ab80071) at 1/500 dilution
Lane 1 : Non-transfected 293 cell lysates
Lane 2 : Beta 2 Microglobulin transfected 293 cell lysates
Lysates/proteins at 2 µg per lane.
Anti-beta 2 Microglobulin antibody - C-terminal (ab80071)参考文献
ab80071 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"