Anti-beta 2 Microglobulin抗体(ab6608)


  • 产品名称Anti-beta 2 Microglobulin抗体
    参阅全部 beta 2 Microglobulin 一抗
  • 描述
    兔多克隆抗体to beta 2 Microglobulin
  • 经测试应用适用于: WB, IP, ELISA, Conjugation, Dot blot, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    b 2-Microglobulin [Human Urine]

  • 常规说明The antibody reacts with b2-microglobulin isolated from human urine showing a 12.8 kDa band under non-reducing condition of SDS-PAGE.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 0.878% Sodium chloride, 0.424% Potassium phosphate
  • Concentration information loading...
  • 纯度IgG fraction
  • 纯化说明This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified b 2-Microglobulin [Human Urine].
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab6608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Conjugation Use at an assay dependent concentration.
Dot blot Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration. PubMed: 20017200


  • 功能Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
  • 疾病相关Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
    Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.
  • 序列相似性Belongs to the beta-2-microglobulin family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • 翻译后修饰Glycation of Ile-21 is observed in long-term hemodialysis patients.
  • 细胞定位Secreted. Detected in serum and urine.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B2M antibody
    • B2MG_HUMAN antibody
    • Beta 2 microglobin antibody
    • Beta 2 microglobulin antibody
    • Beta 2 microglobulin precursor antibody
    • Beta chain of mhc class 1 proteins antibody
    • Beta chain of MHC class I molecules antibody
    • Beta-2-microglobulin form pI 5.3 antibody
    • CDABP0092 antibody
    • Hdcma22p antibody
    see all

Anti-beta 2 Microglobulin antibody (ab6608)参考文献

This product has been referenced in:
  • Kotsiou E  et al. Dimerization of soluble disulfide trap single-chain major histocompatibility complex class I molecules dependent on Peptide binding affinity. Antioxid Redox Signal 15:635-44 (2011). WB ; Human . Read more (PubMed: 21050141) »
  • Vecchi C  et al. Huh-7: a human "hemochromatotic" cell line. Hepatology 51:654-9 (2010). ICC/IF ; Human . Read more (PubMed: 20017200) »

See all 4 Publications for this product

Product Wall

Thank you for yur enquiry and your interest in our products. The antibody reacts with b2-microglobulin isolated from human urine showing a 12.8 kDa band under non-reducing condition of SDS-PAGE.

Thank you for your patience. Actually we've never seen a blot like this before. We consulted with a couple of senior staffs in our company. We came out several suggestions as following: 1. Filter the whatever blocking reagent they use, may add...

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Thank you for your e-mail. We have solved several vial form exactly the same batch number without any problem. Has this customer performed an experiment using different primary antibodies on the same blot? Has he done a head-to-head experiment? ...

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