Anti-beta 2 Microglobulin抗体(ab31137)

概述

  • 产品名称Anti-beta 2 Microglobulin抗体
    参阅全部 beta 2 Microglobulin 一抗
  • 描述
    鸭多克隆抗体to beta 2 Microglobulin
  • 特异性A single arc was shown while the antibody was reacting with part pure human beta 2 microglobulin by Immunoelectrophoresis. Nothing was shown when the antibody reacted with normal human serum. Similar specific reactions were observed when the antibody was tested by western blot assay.
  • 经测试应用适用于: WB, Immunoelectrophoresis, ELISA, Immunodiffusionmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified) (Human): beta 2 Microglobulin

  • 常规说明ab31137 is an IgY (delta Fc).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.14M Sodium chloride, 10mM PBS, pH 7.2
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab31137 purity was determined by SDS-PAGE(blue stain), showing that the IgY (deltaFc) constitute was >90% of total protein.
  • 克隆多克隆
  • 同种型IgY
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab31137 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 14 kDa.
Immunoelectrophoresis Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
Immunodiffusion Use at an assay dependent dilution.

靶标

  • 功能Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
  • 疾病相关Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
    Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.
  • 序列相似性Belongs to the beta-2-microglobulin family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • 翻译后修饰Glycation of Ile-21 is observed in long-term hemodialysis patients.
  • 细胞定位Secreted. Detected in serum and urine.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B2M antibody
    • B2MG_HUMAN antibody
    • Beta 2 microglobin antibody
    • Beta 2 microglobulin antibody
    • Beta 2 microglobulin precursor antibody
    • Beta chain of mhc class 1 proteins antibody
    • Beta chain of MHC class I molecules antibody
    • Beta-2-microglobulin form pI 5.3 antibody
    • CDABP0092 antibody
    • Hdcma22p antibody
    see all

Anti-beta 2 Microglobulin antibody (ab31137)参考文献

ab31137 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab31137.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"