Anti-beta 2 Defensin/BD-2抗体(ab63982)
Key features and details
- Rabbit polyclonal to beta 2 Defensin/BD-2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-beta 2 Defensin/BD-2抗体
参阅全部 beta 2 Defensin/BD-2 一抗 -
描述
兔多克隆抗体to beta 2 Defensin/BD-2 -
宿主
Rabbit -
特异性
Human 7 kDa beta 2 Defensin / hBD-2.
-
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Concentration information loading...
-
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab63982于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P | (1) |
1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
|
说明 |
---|
IHC-P
1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
-
功能
Has antibacterial activity. -
组织特异性
Expressed in the skin and respiratory tract. -
序列相似性
Belongs to the beta-defensin family. LAP/TAP subfamily. -
细胞定位
Secreted. - Information by UniProt
-
数据库链接
- Entrez Gene: 100289462 Human
- Entrez Gene: 1673 Human
- Omim: 602215 Human
- SwissProt: O15263 Human
- Unigene: 105924 Human
- Unigene: 721744 Human
-
别名
- BD 2 antibody
- BD-2 antibody
- BD2 antibody
see all
图片
-
ab63982 (1/500) staining beta 2 Defensin/BD-2 in human tonsil using an automated system (DAKO Autostainer Plus). Using this protocol there is strong cytoplasmic staining of a small population of cells within the tonsillar tissue.
Sections were rehydrated and antigen retrieved with the Dako 3 in 1 AR buffer EDTA pH 9.0 in a DAKO PT link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 mins. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 min and detected with Dako envision flex amplification kit for 30 minutes. Colorimetric detection was completed with Diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that, for manual staining, optimization of primary antibody concentration and incubation time is recommended. Signal amplification may be required. -
ab63982 staining beta 2 Defensin/BD-2 in human pancreatic tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue was fixed with formaldehyde and a heat mediated antigen retrieval step was performed. Samples were then incubated with the primary antibody at a 1/500 dilution for 1 hour at 25°C. An undiluted HRP-conjugated goat polyclonal was used as secondary antibody.
数据表及文件
-
SDS download
-
Datasheet download
文献 (20)
ab63982 被引用在 20 文献中.
- Dajnoki Z et al. Primary alterations during the development of hidradenitis suppurativa. J Eur Acad Dermatol Venereol 36:462-471 (2022). PubMed: 34724272
- Lebeau A et al. HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nat Commun 13:1076 (2022). PubMed: 35228537
- Šerstņova K et al. Expression of anti-inflammatory markers IL-2, IL-10, TGF-β1, βDEF-2, βDEF-3 and Cathelicidin LL37 in dairy cattle milk with different health status of the udder. Pol J Vet Sci 25:237-248 (2022). PubMed: 35861957
- Meloni M et al. Reproducing the scalp microbiota community: co-colonization of a 3D reconstructed human epidermis with C. acnes and M. restricta. Int J Cosmet Sci 43:235-245 (2021). PubMed: 33469935
- Woodby B et al. Cutaneous antimicrobial peptides: New "actors" in pollution related inflammatory conditions. Redox Biol 41:101952 (2021). PubMed: 33839421