Anti-beta 1 Adrenergic Receptor抗体(ab64996)

概述

  • 产品名称Anti-beta 1 Adrenergic Receptor抗体
    参阅全部 beta 1 Adrenergic Receptor 一抗
  • 描述
    兔多克隆抗体to beta 1 Adrenergic Receptor
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from internal sequence of human beta 1 Adrenergic Receptor.

  • 阳性对照
    • Extracts from HT-29 cells.

性能

应用

Our Abpromise guarantee covers the use of ab64996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

靶标

  • 功能Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
  • 结构域The PDZ domain-binding motif mediates competitive interactions with GOPC, MAGI3 and DLG4 and plays a role in subcellular location of the receptor.
  • 翻译后修饰Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
  • 细胞定位Cell membrane. Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADR B1 antibody
    • ADRB 1 antibody
    • ADRB1 antibody
    • ADRB1_HUMAN antibody
    • ADRB1R antibody
    • Adrenergic beta 1 receptor antibody
    • Adrenoceptor beta 1 antibody
    • B1AR antibody
    • Beta 1 adrenoceptor antibody
    • Beta 1 adrenoreceptor antibody
    • Beta-1 adrenergic receptor antibody
    • Beta-1 adrenoceptor antibody
    • Beta-1 adrenoreceptor antibody
    • BETA1AR antibody
    • RHR antibody
    see all

Anti-beta 1 Adrenergic Receptor antibody 图像

  • All lanes : Anti-beta 1 Adrenergic Receptor antibody (ab64996) at 1/500 dilution

    Lane 1 : Extracts from HT-29 cells (5-30 µg of total protein)
    Lane 2 : Extracts from HT-29 cells (5-30 µg of total protein) with 5-10µg of the immunising peptide


    Predicted band size : 51 kDa
    Observed band size : 51 kDa

Anti-beta 1 Adrenergic Receptor antibody (ab64996)参考文献

ab64996 has not yet been referenced specifically in any publications.

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