概述

  • 产品名称Anti-Beclin 1抗体
    参阅全部 Beclin 1 一抗
  • 描述
    兔多克隆抗体to Beclin 1
  • 经测试应用适用于: WB, ELISA, IHC-P, ICCmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    A 16 amino acid KLH conjugated synthetic peptide from near the C-terminus of Human Beclin 1.

  • 阳性对照
    • A431 cells, Human Heart, Kidney and Lung (Respiratory Epithelium) tissue

性能

应用

Our Abpromise guarantee covers the use of ab109631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 52 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC Use a concentration of 1 µg/ml.

靶标

  • 功能Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the beclin family.
  • 细胞定位Golgi apparatus > trans-Golgi network membrane. Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • APG6 antibody
    • ATG 6 antibody
    • ATG6 antibody
    • ATG6 autophagy related 6 homolog antibody
    • Bcl-2-interacting protein beclin antibody
    • Beclin 1 (coiled coil moesin like BCL2 interacting protein) antibody
    • Beclin 1 autophagy related antibody
    • Beclin-1 antibody
    • Beclin1 antibody
    • BECN 1 antibody
    • Becn1 antibody
    • BECN1_HUMAN antibody
    • Coiled coil myosin like BCL2 interacting protein antibody
    • Coiled-coil myosin-like BCL2-interacting protein antibody
    • GT197 antibody
    • Protein GT197 antibody
    • VPS 30 antibody
    • VPS30 antibody
    see all

Anti-Beclin 1 antibody 图像

  • Lane 1 : Anti-Beclin 1 antibody (ab109631) at 0.5 µg/ml
    Lane 2 : Anti-Beclin 1 antibody (ab109631) at 1 µg/ml
    Lane 3 : Anti-Beclin 1 antibody (ab109631) at 2 µg/ml

    Lane 1 : A431 cell lysate
    Lane 2 : A431 cell lysate
    Lane 3 : A431 cell lysate


    Predicted band size : 52 kDa
  • Human Heart (formalin-fixed, paraffin-embedded) stained with ab109631 at a concentration of 2.5 ug/ml.
  • Human Kidney (formalin-fixed, paraffin-embedded) stained with ab109631 at a concentration of 2.5 ug/ml.
  • Human Lung, Respiratory Epithelium (formalin-fixed, paraffin-embedded) stained with ab109631 at a concentration of 2.5 ug/ml.
  • Immunocytochemistry staining of A431 cells using ab109631 at a concentration of 1 µg/ml.

Anti-Beclin 1 antibody (ab109631)参考文献

ab109631 has not yet been referenced specifically in any publications.

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