Anti-BCRP/ABCG2抗体- Carboxyterminal end (ab64757)

概述

  • 产品名称Anti-BCRP/ABCG2抗体- Carboxyterminal end
    参阅全部 BCRP/ABCG2 一抗
  • 描述
    兔多克隆抗体to BCRP/ABCG2 - Carboxyterminal end
  • 特异性This antibody reacts with BCRP/ABCG2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    This information is considered to be commercially sensitive

  • 阳性对照
    • HepG2 cell line lysates

性能

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应用

Our Abpromise guarantee covers the use of ab64757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
ELISA 1/1000.

靶标

  • 功能Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
  • 组织特异性Highly expressed in placenta. Low expression in small intestine, liver and colon.
  • 序列相似性Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
    Contains 1 ABC transmembrane type-2 domain.
    Contains 1 ABC transporter domain.
  • 翻译后修饰Glycosylation-deficient ABCG2 is normally expressed and functional.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ABC transporter antibody
    • ABC15 antibody
    • ABCG 2 antibody
    • ABCG2 antibody
    • ABCG2_HUMAN antibody
    • ABCP antibody
    • ATP binding cassette sub family G (WHITE) member 2 antibody
    • ATP binding cassette transporter G2 antibody
    • ATP-binding cassette sub-family G member 2 antibody
    • BCRP antibody
    • BCRP1 antibody
    • BMDP antibody
    • Breast cancer resistance protein antibody
    • CD338 antibody
    • CDw338 antibody
    • CDw338 antigen antibody
    • EST157481 antibody
    • GOUT1 antibody
    • MGC102821 antibody
    • Mitoxantrone resistance associated protein antibody
    • Mitoxantrone resistance-associated protein antibody
    • MRX antibody
    • Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody
    • MXR antibody
    • MXR1 antibody
    • Placenta specific ATP binding cassette transporter antibody
    • Placenta specific MDR protein antibody
    • Placenta-specific ATP-binding cassette transporter antibody
    • UAQTL1 antibody
    see all

Anti-BCRP/ABCG2 antibody - Carboxyterminal end 图像

  • Anti-BCRP/ABCG2 antibody - Carboxyterminal end (ab64757) at 1/60 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 72 kDa
    Observed band size : 72 kDa

Anti-BCRP/ABCG2 antibody - Carboxyterminal end (ab64757)参考文献

ab64757 has not yet been referenced specifically in any publications.

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