Anti-Bcr-abl抗体[7C6] (FITC) (ab187832)

概述

  • 产品名称
    Anti-Bcr-abl抗体[7C6] (FITC)
    参阅全部 Bcr-abl 一抗
  • 描述
    小鼠单克隆抗体[7C6] to Bcr-abl (FITC)
  • 宿主
    Mouse
  • 偶联物
    FITC. Ex: 493nm, Em: 528nm
  • 特异性
    The antibody recognizes an epitope within the amino acid sequence SSINEEITPRRQS of Bcr-abl.
  • 经测试应用
    适用于: ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment within Human Bcr-abl conjugated to Bovine thyroglobulin. The exact sequence is proprietary. Bcr686 thyroglobulin conjugate
    Database link: A9UF07

性能

应用

Our Abpromise guarantee covers the use of ab187832 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration.

靶标

  • 相关性
    The BCR gene is involved in the 9:22 translocation that generates the Philadelphia chromosome both in chronic myeloid leukemia (CML) and in a proportion of cases of acute lymphocytic leukemia (ALL). A 5' bcr sequence becomes fused to an abl sequence (including tyrosine kinase domain sequences) from chromosome 9 and results in the production of a chimaeric BCR-ABL protein with enhanced kinase activity. These antibodies may be useful for studies of the oncogene and have potential diagnostic and prognostic applications.
  • 数据库链接
  • 别名
    • ALL antibody
    • BCR ABL fusion antibody
    • BCR ABL fusion protein antibody
    • BCR antibody
    • BCR/ABL fusion antibody
    • BCR/ABL fusion protein antibody
    • Bcr/c abl oncogene protein antibody
    • BCRe18/ABL1e3 fusion protein antibody
    • Breakpoint cluster region antibody
    • CML antibody
    see all

文献

ab187832 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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