功能Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.
组织特异性Detected in testis and prostate. Detected at lower levels in peripheral blood leukocytes and spleen.
序列相似性Belongs to the BCOR family. Contains 3 ANK repeats.
翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.