Anti-BCMA抗体[MM0108-3D44] (ab89152)

概述

  • 产品名称Anti-BCMA抗体[MM0108-3D44]
    参阅全部 BCMA 一抗
  • 描述
    大鼠单克隆抗体[MM0108-3D44] to BCMA
  • 经测试应用适用于: WB, Inhibition Assaymore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment (Human) - extracellular domain

性能

应用

Our Abpromise guarantee covers the use of ab89152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 20 kDa.
Inhibition Assay Use at an assay dependent dilution.

靶标

  • 功能Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
  • 组织特异性Expressed in mature B-cells, but not in T-cells or monocytes.
  • 疾病相关Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
  • 序列相似性Contains 1 TNFR-Cys repeat.
  • 细胞定位Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B cell maturation antigen antibody
    • B cell maturation factor antibody
    • B cell maturation protein antibody
    • B-cell maturation protein antibody
    • BCM antibody
    • BCMA antibody
    • CD269 antibody
    • CD269 antigen antibody
    • TNFRSF17 antibody
    • TNR17_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 17 antibody
    see all

Anti-BCMA antibody [MM0108-3D44] (ab89152)参考文献

ab89152 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89152.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"