Anti-BCL9L抗体(ab113110)

概述

  • 产品名称Anti-BCL9L抗体
  • 描述
    兔多克隆抗体to BCL9L
  • 特异性ab113110 is predicted to not cross-react with other BCL family members. At least four isoforms of BCL9L are known to exist; ab113110 will detect all four.
  • 经测试应用适用于: ICC, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide containing a 20 amino acid sequence from the N terminal region of Human BCL9L (NP_872363).

  • 阳性对照
    • HeLa cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99.98% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab113110 is purified by affinity chromatography via a peptide column.
  • 克隆多克隆
  • 同种型IgG

相关产品

应用

Our Abpromise guarantee covers the use of ab113110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC Use a concentration of 10 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 157 kDa.

靶标

  • 功能Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1.
  • 组织特异性Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.
  • 序列相似性Belongs to the BCL9 family.
  • 结构域Tne C-terminal domain is important for its transactivation activity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B-cell CLL antibody
    • B-cell CLL/lymphoma 9-like protein antibody
    • B-cell lymphoma 9-like protein antibody
    • B9L antibody
    • BCL9-2 antibody
    • BCL9-like protein antibody
    • BCL9-related beta-catenin-binding protein antibody
    • Bcl9l antibody
    • BCL9L_HUMAN antibody
    • DLNB11 antibody
    • Nuclear co factor of beta catenin signalling antibody
    • Protein BCL9-2 antibody
    see all

Anti-BCL9L antibody 图像

  • All lanes : Anti-BCL9L antibody (ab113110) at 1 µg/ml

    Lane 1 : HeLa cell lysate
    Lane 2 : HeLa cell lysate with Blocking peptide


    Predicted band size : 157 kDa
  • Immunocytochemistry of Bcl9L in HeLa cells with ab113110 at 10 ug/mL.

Anti-BCL9L antibody (ab113110)参考文献

ab113110 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Mouse Cell lysate - whole cell (4T1 - mouse breast cancer cell line)
Gel Running Conditions Reduced Denaturing (4-12%)
Loading amount 30 µg
Specification 4T1 - mouse breast cancer cell line
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 23°C
Username

Abcam user community

Verified customer

提交于 May 12 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"