概述

  • 产品名称Anti-Bcl2A1抗体
    参阅全部 Bcl2A1 一抗
  • 描述
    兔多克隆抗体to Bcl2A1
  • 特异性This antibody is specific for Bcl2A1.
  • 经测试应用适用于: IHC-P, ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A 14 amino acid peptide from near the carboxy terminus of human Bcl2A1

  • 阳性对照
    • Human kidney tissue lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab45413 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 10 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 20 kDa.

靶标

  • 功能Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.
  • 组织特异性Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
  • 序列相似性Belongs to the Bcl-2 family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACC 1 antibody
    • ACC 2 antibody
    • B2LA1_HUMAN antibody
    • Bcl 2 related protein A1 antibody
    • Bcl-2-like protein 5 antibody
    • Bcl-2-related protein A1 antibody
    • BCL2 related protein A1 antibody
    • Bcl2-L-5 antibody
    • BCL2A1 antibody
    • BCL2L5 antibody
    • BFL1 antibody
    • GRS antibody
    • HBPA1 antibody
    • Hematopoietic BCL2 related protein A1 antibody
    • Hemopoietic specific early response protein antibody
    • Hemopoietic-specific early response protein antibody
    • Protein BFL 1 antibody
    • Protein BFL-1 antibody
    • Protein GRS antibody
    see all

Anti-Bcl2A1 antibody 图像

  • All lanes : Anti-Bcl2A1 antibody (ab45413) at 1 µg/ml

    Lane 1 : Human kidney tissue lysate
    Lane 2 : Human lung tissue lysate


    Predicted band size : 20 kDa
  • ab45413 at 10µg/ml staining Bcl2A1 in mouse kidney tissue by IHC

  • Immunofluorescence of Bfl-1 in Mouse Kidney cells using ab45413 at 20 ug/ml.

Anti-Bcl2A1 antibody (ab45413)参考文献

This product has been referenced in:
  • Jauharoh SN  et al. SS-A/Ro52 promotes apoptosis by regulating Bcl-2 production. Biochem Biophys Res Commun 417:582-7 (2012). WB ; Human . Read more (PubMed: 22178074) »
  • Fardin P  et al. Induction of epithelial mesenchimal transition and vasculogenesis in the lenses of Dbl oncogene transgenic mice. PLoS One 4:e7058 (2009). IHC-P ; Mouse . Read more (PubMed: 19759912) »

See all 2 Publications for this product

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Catalog number ab45413 anti-Bcl2A1 antibody is specific to isoform 1 of Bfl-1 (per Uniprot Q16548).

I hope this information is helpful to you. Please do not hesitate to contact us if you need any m...

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Abreviews
Application Western blot
Sample Human Cell lysate - whole cell (HL60)
Loading amount 10 µg
Specification HL60
Gel Running Conditions Reduced Denaturing
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
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提交于 Jun 20 2007

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"