Anti-BCCIP抗体- Carboxyterminal end (ab71453)

概述

  • 产品名称
    Anti-BCCIP抗体- Carboxyterminal end
    参阅全部 BCCIP 一抗
  • 描述
    兔多克隆抗体to BCCIP - Carboxyterminal end
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 阳性对照
    • A2058 nuclear lysate

性能

应用

Our Abpromise guarantee covers the use of ab71453 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately isoform 3: 33 kDa (predicted molecular weight: 36 kDa).

靶标

  • 功能
    May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
  • 组织特异性
    Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.
  • 序列相似性
    Belongs to the BCP1 family.
  • 发展阶段
    Isoform 1 is expressed throughout the cell cycle. Isoform 2 is expressed following mitosis and peaks in the G1/S phase of the cell cycle.
  • 细胞定位
    Nucleus. Colocalizes with BRCA2 in discrete nuclear foci.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bccip antibody
    • BCCIP_HUMAN antibody
    • BCCIPalpha antibody
    • BCCIPbeta antibody
    • BRCA2 and CDKN1A interacting protein antibody
    • BRCA2 and CDKN1A-interacting protein antibody
    • BRCA2 and Cip1/p21 interacting protein antibody
    • Cdk inhibitor p21 binding protein antibody
    • P21 and CDK associated protein 1 antibody
    • P21- and CDK-associated protein 1 antibody
    • Protein TOK-1 antibody
    • Protein TOK1 antibody
    • TOK 1 antibody
    • TOK 1alpha antibody
    • TOK 1beta antibody
    • TOK1 antibody
    see all

Anti-BCCIP antibody - Carboxyterminal end 图像

实验方案

Anti-BCCIP antibody - Carboxyterminal end (ab71453)参考文献

ab71453 has not yet been referenced specifically in any publications.

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